“The joy of discovery is certainly the
liveliest that the mind of man can ever feel”

- Claude Bernard -



Academic Publications


Scientific Publications

1. Winther, K., Warholm, L., Campbell-Tofte, J., Marstrand, K. (2018) Effect of Rosa canina L (Rose-hip) on cold during winter season in a middle-class population: A randomized, double-blinded, placebo-controlled trial. Journal of Herbal Medicine (In Press)

2. Winther, K., Campbell-Tofte, J.,  Motawei. A.M., Pedersen, F., Roos, S.B., Hansen, A.S.V., Fornitz, G.G., Killi, M., Gerhardsen, G. (2018) A double-blinded, randomized, placebo controlled, parallel study of pollen pistil extract (Sèrèlys) on women reporting irritability as predominant PMS symptom. Journal of Herbal Medicine (In Press)

3. Marstrand, K., Campbell-Tofte, J. (2016) The role of rose hip (Rosa canina L) powder in alleviating arthritis pain and inflammation: part II, animal and human studies. Botanics: Targets and Therapy, 6:59-73. DOI

4. Winther, K., Hansen, A.S., Campbell-Tofte, J. (2016) Bioactive ingredients of rose hips (Rosa canina L) with special reference to antioxidative and anti-inflammatory properties: part I, in vitro studies. Botanics: Targets and Therapy, Volume 2016:11-23. DOI

5. Winther, K., Marstrand, K., Campbell-Tofte, J., Hansen, P. (2015) King Lear: “Nothing can come of nothing: speak again.”: The impact of PLACEBO on pain & physical activity in patients with osteoarthritis. European Journal of Integrative Medicine. Vol 7, Supplement 1:28.

6. Winther, K., Campbell-Tofte, J. (2015) Rose hip powder made from a subspecies of Rosa canina (containing seeds and shells) reduces symptoms of osteoarthritis and the need for pain killers. European Journal of Integrative Medicine. Vol 7, Supplement 1:28.

7. Campbell-Tofte, J., Mølgaard, P., Winther, K. (2015) Rapid and cost-effective assessments of the safety & benefits of herbal remedies with using Systems Biology technology (Fast-Pharma). European Journal of Integrative Medicine. Vol 7, Supplement 1:32-33

8. Winther, K., Campbell-Tofte, J., Hansen, P. (2013) Rose Hip Powder That Contains the Natural Amount of Shells and Seeds Alleviates Pain in Osteoarthritis of the Dominant Hand—A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Clinical Trial. Open Journal of Rheumatology and Autoimmune Diseases, Vol. 3 (3) 172-180. doi: 10.4236/ojra.2013.33027.

9. Campbell-Tofte, J., Mølgaard P., Winther K. (2012) Harnessing the potential clinical use of medicinal plants as anti-diabetic agents. Botanics: Targets and Therapy 2: 7–19. DOI

10. Campbell-Tofte, J.I.A., Mølgaard, P., et al. (2011). Randomized and double-blinded pilot clinical study of the safety and anti-diabetic efficacy of the Rauvolfia-Citrus tea, as used in Nigerian Traditional Medicine. Journal of Ethnopharmacology, 133:402–411. PMID: 20955771 DOI: 10.1016/j.jep.2010.10.013

11. Campbell-Tofte, J., Hansen, S.H., Mu, H., Mølgaard, P. (2007) Increased lipids in non-lipogenic tissues are indicators of the severity of type II diabetes in mice. Prostaglandins, Leukotrienes and Essential Fatty acids, 76: 9-18. PMID: 17098406 DOI: 10.1016/j.plefa.2006.09.002

12. Campbell, J.I.A, Mortensen A., Mølgaard P. (2006) Tissue lipid lowering-effect of a traditional Nigerian anti-diabetic infusion of Rauwolfia vomitoria foliage & Citrus aurantium fruit. Journal of Ethnopharmacology, 104: 379-386. PMID: 16455217 DOI: 10.1016/j.jep.2005.12.029

13. Nielsen, C.K., Campbell, J.I.A., Öhd, J.F., Mörgelin, M., Riesbeck, K., Landberg, G., Sjölander, A. (2005) A novel localization of the G-protein coupled CysLT1 receptor in the nucleus of colorectal adenocarcinoma cells. Cancer Research, 65: 732-742.

14. Öhd, J.F., Nielsen, C.K., Campbell, J., Landberg, G., Löfberg, H. and Sjölander, A. (2003) Expression of the Leukotriene D4 receptor CysLT1, COX-2, and other cell survival factors in colorectal adenocarcinomas. Gastroenterology, 124: 57-70. PMID: 12512030 DOI: 10.1053/gast.2003.50011

15. Campbell-Tofte, Joan: Design and Implementation of a portable Neural Network Interpreter. Master of Science thesis, IT University of Copenhagen (2003).

16. Bagge, N., Ciofu O, Hentzer M, Campbell, J.I.A., Givskov, M., and Høiby, N. (2002) Constitutive high expression of chromosomal beta-lactamase of chromosomal beta-lactamase in Pseudomonas aeruginosa caused by a new insertion sequence (IS1669) located in ampD. Antimicrobial Agents Chemotherapy, 46: 3406-3411. DOI: 10.1128/AAC.46.11.3406-3411.2002

17. Mathee, K., Ciofu, O., Sternberg, C., Lindum, P., Campbell, J.I., Jensen, P., Johnsen A.H. Givskov, M., Ohman, D.E., Molin, S., Høiby, N., and Kharazmi (1999) A. Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: A potential mechanism for virulence activation in the cystic fibrosis lung. Microbiology, 145: 1349-1357. DOI: 10.1099/13500872-145-6-1349

18. Campbell, J.I.A., Ciofu, O. and Høiby, N (1997). Pseudomonas aeruginosa isolates from patients with cystic fibrosis have different beta-lactamase expression phenotypes but are homogenous in their ampC and ampR genetic region. Antimicrobial Agents Chemotherapy 41: 1380-1384. PMCID: PMC163920

19. Campbell, J.I.A., Albrechtsen, M., and Sørensen, J. (1995) Large Pseudomonas specific phages isolated from barley rhizosphere. FEMS Microbiology Ecology 18: 63-74.

20. Campbell, J.I.A., Jacobsen, C.S., and Sørensen, J. (1995) Species variation and plasmid incidence amongst fluorescent Pseudomonas stains isolated from Agricultural and Industrial Soils. FEMS Microbiolgy Ecology 18: 51-62.

21. Boursnell, M.E.G., Green, P.F., Samson, A.C.R., Campbell, J.I.A., Deuter, A.D., Peters, R.W., Millar, N.S., Emmerson, P.T. and Binns, M.M. (1990) A recombinant fowlpox virus expressing the hemagglutinin-neuraminidase gene of Newcastle Disease Virus (NDV) protects chickens against challenge by NDV. Virology 178: 297-300.

22. Boursnell, M.E.G., Green, P.F., Campbell, J.I.A., Deuter, A., Peters, R.W., Tomley, F.M., Samson. A.C.R., Chambers, P. and Binns, M.M. (1990) Insertion of the fusion gene from Newcastle disease virus into a non-essential region in the terminal repeats of fowlpox virus and demonstration of protective immunity induced by the recombinant. Journal of General Virology, 71: 621-628. DOI: 10.1099/0022-1317-71-3-621

23. Binns, M.M., Boursnell, M.E.G., Tomley, F.M. and Campbell, J., (1989) Analysis of the FPV gene encoding the 4B Core Polypeptide and demonstration that it possesses efficient promoter sequences. Virology 170: 288-291.

24. Boursnell, M.E.G., Foulds, I.J., Campbell, J.I. and Binns, M.M. (1988) Non-essential genes in the Vaccinia virus Hind III K fragment: a gene related to serine protease inhibitors and a gene related to the 37K vaccinia major envelope antigen. Journal of General Virology 69: 2995-3003. DOI: 10.1099/0022-1317-69-12-2995

25. Tomley, F.M., Binns, M.M., Campbell, J. and Boursnell, M.E.G. (1988) Sequence analysis of an11.2Kb near-terminal Bam H1 fragment of fowlpox virus. Journal of General Virology, 69: 1025-1040. doi: 10.1099/0022-1317-69-5-1025

26. Binns, M.M., Tomley, F.M., Campbell, J. and Boursnell, M.E.G. (1988) Comparison of a conserved region in fowlpox virus and Vaccinia Virus genomes and the translocation of the fowlpox virus thymidine kinase gene. Journal of General Virology, 69: 1275-1283. DOI: 10.1099/0022-1317-69-6-1275

27. Binns, M.M, Stenzler, L. Tomley, F.M., Campbell, J. and Boursnell, M.E.G. (1987) Identification by a random sequencing strategy of the FPV DNA polymerase gene, its nucleotide sequence and comparison with other viral DNA polymerases. Nucleic Acids Research, 15: 6563-6573.

28. Campbell, J.I.A., Binns, M.M, Tomley, F.M. and Boursnell, M.E.G. (1989) Tandem repeated sequences within the terminal region of the Fowlpox Virus genome. Journal of General Virology, 70: 145-154. doi: 10.1099/0022-1317-70-1-145

29. Campbell, J.I.A., Scahill, S., Gibson, T. and Ambler, R.P. (1989) The phototropic bacterium Rhodopseudomonas capsulata sp 108 encodes an indigenous class-A beta-lactamase. Journal of Biochemistry 260: 803-812. DOI: 10.1042/bj2600803

30. Obi, S.K.C. and Campbell, J.A. (1978) Incidence of colicinogenic E.coli in cattle, goat and sheep. ZBL. Vet. Med. B, 25: 652-656.

Scientific Reports

1. Delprato A, Aransay AM, Kollmus H, Schughart K, Falcon-Perez JM. (2013) Meeting report of the European mouse complex genetics network SYSGENET. Mammalian Genome. 24(5-6):190-7. doi: 10.1007/s00335-013-9458-y.

2. Schughart K; SYSGENET consortium. (2010) SYSGENET: a meeting report from a new European network for systems genetics. Mammalian Genome, 21(7-8):331-336. doi: 10.1007/s00335-010-9273-7.

3. Campbell-Tofte, J. & Mølgaard, P. (2007) Anti-diabetiske te fra nigeriansk folkemedicin. LÆGEMIDDELFORSKNING 2007, DET FARMACEUTISKE FAKULTET, KØBENHAVNS UNIVERSITET; 4-5.

4. Campbell-Tofte, J. (2002) International Development Fund reports: 2001 Summer Course on PCR Techniques. University of Agriculture, Abeokuta (UNAAB), Nigeria. MICROBIOLOGY TODAY, 29-46.

Present & Past Patents
1. United States Patent No.: US 7,579,025 B2; August 25, 2009.Title: Anti-diabetic extract isolated from Rauvolfia vomitoria and Citrus aurantium, and methods of using same. Inventor: Joan Campbell-Tofte

2. US Patent No.: 5374558; December 20, 1994 Title: Fowlpox virus promoter. Inventors: Binns, Matthew M., Boursnell, Michael E. G., Campbell, Joan I. A.

3. US Patent No.: 5332676; July 26, 1994 Title: Avipox virus promoter. Inventors: Binns, Matthew M., Boursnell, Michael E. G., Campbell, Joan I. A.

4. US Patent No.: 5310671; May 10, 1994 Title: Fowlpox virus non-essential regions. Inventors: Binns, Matthew M., Boursnell, Michael E. G., Campbell, Joan I. A., Tomley, Fiona M.

5. US Patent No.: 5182210; January 26, 1993 Title: Fowlpox virus promoters. Inventors: Binns, Matthew M., Boursnell, Michael E. G., Campbell, Joan I. A., Tomley, Fiona M.

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